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Home Pipeline

Pipeline

We’re advancing a pipeline of siRNA therapies across a broad range of indications.

Home Pipeline

Pipeline

We’re advancing a pipeline of siRNA therapies across a broad range of indications.

Therapy Areas

Cardiovascular disease

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • BW-01
  • Cardiovascular disease

  • BW-02
  • Cardiovascular disease

  • ex-China license

  • BW-05
  • Cardiovascular disease

  • global license

  • BW-07
  • Cardiovascular disease

  • BW-15
  • Cardiovascular disease

  • BW-23
  • Cardiovascular disease

  • BW-24
  • Cardiovascular disease

  • BW-32
  • Cardiovascular disease

  • BW-34
  • Cardiovascular disease

Rare disease

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • PKK
  • HAE

  • CFB
  • Complement mediated disease

  • C3
  • Complement mediated disease

  • C5
  • Complement mediated disease

  • MASP-2
  • Complement mediated disease

  • TTR
  • ATTR-CM, ATTR-PN, Stargardt Disease

  • TMPRSS6
  • Hematology disorders

  • BW-40
  • Hemophilia

  • BW-41
  • Genetic rare disease

Viral infection

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • HBV
  • Hepatitis B

Metabolic disease

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • INHBE
  • Obesity, Metabolic syndrome

  • PNPLA3
  • MASH

  • HSD17B13
  • MASH

  • CIDEB
  • MASH

CNS

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • HTT
  • Huntington's disease

  • MAPT
  • Alzheimer's disease

  • APP
  • Alzheimer's disease

  • ApoE
  • Alzheimer's disease

  • SNCA
  • Parkinson's disease

  • LRRK2
  • Parkinson's disease

  • NAV1.7
  • Pain

  • NAV1.8
  • Pain

  • BWS-25
  • Genetic rare disease

Heart

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • BWH-01
  • Heart disease

  • BWH-02
  • Heart disease

  • BWH-03
  • Heart disease

Muscle

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • BWM-02
  • Genetic rare disease

  • BWM-03
  • Genetic rare disease

Adipose

Product Indications Discovery IND enabling Phase I Phase II Phase III Partner
  • ALK7
  • Obesity

  • BWA-02
  • Obesity

  • BWA-03
  • Obesity

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