RNAi is a Nobel Prize-winning technology that utilizes the power of nature's biological mechanisms to silence targeted genes. This innovative technology involves the use of short double stranded RNA molecules and nature’s machinery, the RNA-induced silencing complex, or RISC. Upon RISC loading, sense strand is separated leaving the antisense strand in RISC, which guides the RISC to its target mRNA and degrades the messenger RNA, preventing the production of specific proteins. The RNAi mechanism is catalytic, specific, efficient and durable.